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KMID : 0388220100170040431
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Journal of the Korean Rheumatism Association
2010 Volume.17 No. 4 p.431 ~ p.436
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A Case of Non Secretory Type Multiple Myeloma Associated with Systemic Lupus Erythematosus
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Jeong Yu-Jin
Kim Hyun-Sook
Kim Eun-Jung
Kim Yun-Sung
Park Chi-Young
Shin Bong-Seok
Park Kun
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Abstract
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The development of malignant tumors is a more frequent finding in lupus patients than the general population. However, the incidence of multiple myeloma associated with systemic lupus erythematosus (SLE) is a rare manifestation. SLE is an autoimmune disease characterized by B cell hyperactivity, formation of autoantibodies, and multi-clonal hypergammaglobulinemia. Serum immunoglobulin increases, with a specific increase in IgG, which is due to an increase in autoantibody formation related to extrinsic and intrinsic antigens. We report on a patient with SLE combined with IgG, lambda type nonsecretory multiple myeloma, which was diagnosed with refractory anemia and hypergammaglobulinemia.
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KEYWORD
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Nonsecretory multiple myeloma, Systemic lupus erythematosus
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